Written by Bindu Raichura
Fertility issues have plagued many couples’ lives. The technological advancement and innovation in fertility treatments have helped many couples start a family of their own. In vitro fertilization (IVF) treatments have changed the lives of many families for the better. If you are planning on getting an IVF treatment, you need to know about Preimplantation Genetic Screening (PGS) and Preimplantation Genetic Diagnosis (PGD).
In This Article
PGS is a procedure that screens an embryo to check if it has the right number of chromosomes. A total of 23 pairs of chromosomes are required to make a healthy human baby.
IVF treatments are known for multiple pregnancies. This is because multiple embryos are inserted into the uterus to increase the chances of implantation. When the number of chromosomes is less or more than the required 23 pairs, it can lead to miscarriages. In order to avoid this, fertility centers advise couples to do PGS. The PGS normal embryo success rate is quite high since defective embryos are not implanted.
Unlike PGS, PGD is a procedure that screens the couple’s embryo for any known genetic disease or defective gene that can cause disease. If the male or the female has a family history of certain genetic diseases, they can be carriers of the defective gene. They need not suffer from the disease itself but can have the gene that can pass on the disease to the next generation.
In order to avoid this, PGD is done and the defective gene can also be removed. Some of the diseases the PGD screens are:
The PGD cost is not included in the cost of the IVF treatment. Any IVF treatment cost quoted is generally excluding PGD testing cost. Couples undergoing IVF and PGD need to remember, that they need to consider the entire IVF with PGD cost when they decide to go in for this treatment. This can be quite expensive and even more so if more than one attempt is required.
If budget is indeed a constraint for you, do find out how much does IVF with PGD costs before you sign up for it. Do remember your expenses do not stop here and the entire pregnancy and the baby after will require you to spend constantly.
Since an IVF is an expensive procedure and is done to help couples who are unable to get pregnant naturally, all IVF treatments recommend a PGD. Embryos that have a defective gene are not used in IVF treatments. This increases the IVF success rate and results in healthy pregnancies and babies.
When an embryo with a genetic defect is implanted, not only can it result in a miscarriage, but can also result in a baby being born with genetic disorders or diseases. Science has come a long way and PGD helps couples who are already struggling to conceive, to have a healthy child.
Any testing or medical procedure comes with its own set of disadvantages. Some of the risks involved in PGS and PGD testing are:
Here are a few frequently asked questions regarding PGD and PGS testing:
The PGS helps in determining if the embryo is healthy enough and well-balanced. When a chromosome is missing, it can not only result in a miscarriage. but can result in other genetic disorders like Down Syndrome too. With PGS results, IVF treatments can be more successful.
PGS is not recommended for everyone opting for an IVF. It is recommended only if:
The data on this is not clear as research is being carried out only for women between the age of 39 and 41. Women below 35 are not considered and hence PGS-normal success rate is inconclusive. Also, IVF with miscarriage rate is also unknown.
Any genetic testing is expensive when compared to other medical tests and treatments. However, with an increase in the number of players in this market, the tests are competitively priced. Do your research and choose what suits your budget and needs.