Ovarian hyperstimulation is a syndrome which usually occurs in women who are taking the fertility medications to boost the egg production, particularly in vitro fertilization (IVF) treatment. Since IVF medications aim at development of eggs in the ovary for fertilization, particularly ovulation, one cannot say for sure how much injectable medicine you might need. The excess of this medicine can result in too much of hormones in your ovary, further leading to ovarian hyperstimulation syndrome.
The main cause of ovarian hyperstimulation syndrome (OHSS), is fertility drugs. Generally fertility drugs are used to produce egg sac but sometimes they can cause hyper stimulation of ovaries. This happens when presence of the drugs is more than what your body can handle. As a result, the level of hormones responsible for producing eggs in the ovary increases and too much hormones cause the ovaries to get swollen or enlarged. These enlarged ovaries then start releasing chemicals into the blood stream which ultimately start leaking fluid into the body.
Sometimes that leaked fluid reaches heart, lungs and various other organs and become a serious health problem resulting in grave consequences.
In majority of the cases it occurs during fertility treatment when an injection of human chorionic gonadotropin (hCG) is given. In very rare cases, OHSS can happens when women are taking oral medications during fertility treatments.
The common symptoms associated with OHSS is abdominal swelling, pain, nausea and vomiting, On the basis of clinical manifestation symptoms of OHSS are divided into three categories:
These symptoms can often be noticed between 10 days of taking an injectable medication to induce ovulation. Ovarian hyperstimulation syndrome is less pronounced in women who take fertility drugs by mouth, such as clomiphene (Clomid, Serophene). In the event that you do become pregnant, these symptoms may last longer and may worsen as well.
The Risk of OHSS is mainly to the women who-
In majority of the cases mild symptoms are observed in almost every women who are taking the fertility treatment but they generally disappear after sometime but you should consult your doctor if symptoms increase in intensity or persist for longer period of time.
The diagnosis of ovarian hyperstimulation syndrome is based on a physical exam, an ultrasound and a blood test. Increase in weight and waist size, bigger ovaries with large fluid-filled cysts and certain blood tests will enable your doctor to determine whether you have OHSS and the further course of action. The treatment is aimed at keeping you comfortable, and avoiding complications, very much so if you have conceived already. A week or two is all it takes to resolve OHSS unless you are pregnant. Pregnancy may increase your resolution time with OHSS.
Controlled ovarian hyperstimulation (COH) involves careful monitoring of fertility agents that are designed to induce ovulation through fertility medications via IVF. The release of multiple follicles can be used in in vitro fertilization (IVF). This can be achieved by either or both injectable or oral assisted fertility medications. For women with irregular menstruation cycles, COH aims at producing 1 mature follicle and restore normal ovulatory function. In a woman whose cycles are regular and ovulation happens every month, COH increases the pregnancy rates by producing 2-3 mature follicles every month. This is also known as a process to ‘superovulate’ the women, as pregnancy chances increase from one a month to 2 to 3 times a month. Though the success rate is to the tune of 20%, a lot is dependent on the age and fertility diagnosis of the couple.
Please keep in mind there is no specific treatment for OHSS and there is no treatment which can reverse the OHSS. Ovarian hyperstimulation syndrome generally resolves on its own within a week or two and treatment mostly include keeping you comfortable, decreasing ovarian activity and avoiding complications.