Written by Sindhuja Prabhu
Pregnancy is a wonderful phase in every woman’s life. For some women, though, this phase can be riddled with complications. Pregnant women with inherited conditions need to take extra care when pregnant. Thalassemia during pregnancy is one such condition that may need extra care and monitoring to ensure safe delivery.
Women with thalassemia may need to be under a doctor’s care right from the time they plan to get pregnant. Natural conception may be difficult and medically induced ovulation may be needed to get pregnant. From this stage, through pregnancy, complications like anaemia can interfere with a healthy pregnancy. So, what happens when a woman with thalassemia gets pregnant and what course of action is needed? Read the article to know more.
In This Article
Thalassemia in pregnancy is a condition where the red blood cells produced in the body are low and in turn, affects the haemoglobin level in the blood. When the haemoglobin level is too low, it can result in anaemia.
For a pregnant woman who is creating a whole new human being inside her, the haemoglobin level is very important.
Are you wondering if you have thalassemia in pregnancy?
Some of the symptoms are:
Since thalassemia leads to a drop in hemoglobin levels, the symptoms are similar to anemia. Many pregnant women suffer from low hemoglobin levels. Hence it is easy to get it and pregnancy-related anemia confused.
So, what are the causes for this genetic blood disorder in pregnancy? Can it be avoided?
Sadly, the answer is no, it cannot be avoided. This is because thalassemia is a genetically inherited condition. Women with a family history of thalassemia are at a higher risk of suffering from thalassemia in pregnancy.
Sometimes, in rare cases where a gene mutation occurs, parents can pass on defective genes to the fetus. Hence a parent without thalassemia in pregnancy can still pass down a gene change that can lead to improper functioning of the gene, thus resulting in thalassemia in pregnancy.
The only way to know if you are indeed suffering from it is to get a carrier screening test. Your partner and you can both get checked for thalassemia to ensure you are not passing it down to the fetus. This test can not only ascertain if you have thalassemia itself but can also find out if you have the defective gene that can be passed on and result in it.
A carrier screening test for thalassemia can show what type of thalassemia the pregnant woman has (if there are symptoms and signs that she, in fact, has thalassemia).
Every human has four genes that help his body make Alpha-Globin. We get two from each of our parents. Alpha thalassemia is a condition where there is a change in the alpha-globin.
Alpha thalassemia is of four kinds, namely:
When there is an alpha thalassemia gene change or a gene is missing, it results in this type of thalassemia in pregnancy. This makes your fetus a carrier of thalassemia, meaning it can be passed on to the next generation. However, one may not show any symptoms of thalassemia.
Also known as a thalassemia trait, happens when there are two genes missing or gene changes. When it comes to thalassemia minor and pregnancy, sometimes mild symptoms of anemia can be seen.
When there are three genes missing or gene changes, this type occurs. Your fetus, once born, might feel anemic and might also develop complications later.
When there are four missing genes or gene changes this kind of alpha thalassemia, also known as hydrops fetalis, occurs. This is by far the most serious kind of thalassemia that can even result in stillbirth.
Beta Globin is made by two genes that are derived from each parent. When there are changes in genes that make this beta-globin, it can cause beta-thalassemia.
The three variations of beta-thalassemia are:
This is also known as the beta-thalassemia trait. It happens when there is just one gene change. You may have mild anemia or no symptoms at all. This gene can be passed on to your fetus.
When there are two gene changes this type of beta-thalassemia occurs. Most times this can cause mild anemia.
When there are two gene changes, this type of thalassemia, also known as Cooley’s Anemia, can occur. If not treated in time, this serious type of thalassemia can cause a lot of complications. Unfortunately, this can be passed on to your fetus too. When affected by beta-thalassemia major, one can look normal initially but might develop complications such as liver, bone, or heart problems, later in life.
If you or your children have thalassemia, the best treatment you might be suggested is a blood transfusion. Some of the other treatments that can be suggested are iron chelation therapy or a bone marrow transplant.
Pregnancy is a tricky period to treat any disease. The simple reason is that the body undergoes a lot of changes during pregnancy and it is very difficult to ascertain the levels of various hormones and other components in the body.
If you are at risk of developing or already have thalassemia, one of the go-to treatments your doctor would opt for is prescribing folic acid supplements. Folic acid is very important for a healthy pregnancy and thus is generally prescribed for all pregnant women.
Unless there have been cases of thalassemia or thalassemia in pregnancy in your family, or your doctor suspects it, you need not worry about this health complication in pregnancy.
Read Also: Iron Deficiency Anemia During Pregnancy
Sindhuja, a mother of two, is an obsessive mom with a keen interest in psychology, especially child psychology. Her quest for knowledge and way with words led her to become a passionate content writer. She transformed her love for writing into a full-fledged career which incidentally also turned up being the perfect stress buster for the last 5 years.Read more.
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