Written by Sindhuja Prabhu
Did your doctor just diagnose your child with nephrotic syndrome? If yes, then it means your child’s kidneys are not functioning up to the mark. If you are not sure what exactly your child is suffering from, we are here to clear all your doubts.
Each organ in our body has a unique function and even if one of them doesn’t function properly, it can have consequences on the rest of the body. When the kidneys don’t function properly, it can lead to nephrotic syndrome. Read on to know more.
In This Article
Nephrotic syndrome is when the kidney malfunctions and leaks too much albumin into the urine. Albumin is a type of protein, and a high concentration of this protein in the urine indicates either one or both kidneys are not functioning properly.
The kidney consists of many glomerulus – a network or coil of tiny blood vessels. The main function of these glomeruli is to filter the blood and pass out all the waste materials. When these glomeruli stop functioning properly, it leads to nephrotic syndrome.
The child may have the following symptoms if suffering from this illness –
We can classify it in different ways – the way they occur and how they develop.
Idiopathic – The cause is unknown. Most children with nephrotic syndrome suffer from the idiopathic kind.
Secondary – When other health conditions impact the kidneys and lead to nephrotic syndrome.
Congenital – When the syndrome is present from birth. This is a very rare condition caused by genetic abnormality. This type can be aggressive, requiring the child to undergo a kidney transplant within the first few years of their lives.
MCD – Minimal Change Disease is when the tissues and the kidneys both look normal and may have very minimal changes when inspected under a microscope.
FSGS – Focal Sclerosis is a more aggressive type of this disease that may not respond well to steroids. The child might need multiple biopsies and continuous medication to keep the condition under control.
In most cases of nephrotic syndrome in children, it is idiopathic, meaning the cause is unknown. In rare cases, certain viral infections can affect the kidneys, leading to this disorder in children.
A child is at a higher risk of nephrotic syndrome if-
If your child is suffering from nephrotic syndrome, you may notice one or more of the following symptoms. Remember, different types of nephrotic syndromes can have different effects on the child. The signs and symptoms can also vary from child to child. Some of the symptoms are-
When you notice any of the symptoms and consult your pediatrician, they will do the following to confirm a diagnosis of this illness-
To understand if it could be congenital or if there are other health issues that could be impacting the kidneys.
A urine test will check the protein levels in the urine. Next will be a blood test to check for protein levels and cholesterol in the blood.
To check the size and shape of the kidney, check for masses or cysts in the kidney, and also check for other problems.
If the kidney tissue does not look normal, the doctor will ask for a sample. The technician will analyze the sample under a microscope to understand the health of the kidneys.
In most cases, the child will get better and grow out of this illness as they reach adulthood. However, in rare cases, it can lead to the following complications-
If the kidneys are unable to filter the blood properly, it can lead to a loss of important proteins responsible for preventing blood clots. As a result, more clots can develop.
Accumulation of fluids in the body can increase blood pressure.
A lack of albumin in the blood will trigger the liver to produce more albumin along with cholesterol and triglycerides. Thus increasing their levels in the blood.
When kidneys don’t function properly, it increases the risk of infections.
When kidneys don’t filter the wastes effectively, the wastes will build up in the blood requiring external intervention such as dialysis.
When blood does not have sufficient protein, it can lead to low blood protein, anemia, low vitamin D levels, and malnutrition. It can even lead to weight loss but edema may make it difficult to identify this.
Different types of nephrotic syndrome have different treatments. In most cases, the child is put on prednisolone, a steroid medicine. The duration and dosage varies from case to case.
If it is due to the impact of some underlying health condition on the kidneys, doctors will address the issue first. They will prescribe medications and treatments to clear up the health issue and reassess the child’s kidneys after a few days.
If the nephrotic syndrome is FSGS (Focal Sclerosis), the doctor might try different medications. They will most likely stick to the medicine the child responds to. In most cases, the child will have to stay on these medications forever, as FSGS can relapse.
If it is MCD (Minimal Change Disease), the doctor will prescribe medications until the syndrome goes into remission. If there is a relapse, the doctor will reassess and prescribe medications accordingly.
You cannot always prevent nephrotic syndrome in children as most are idiopathic or congenital, meaning it could be genetic.
You can do the following to prevent damage to the glomeruli which in turn can lead to nephrotic syndrome-
Nephrotic syndrome in children is mostly idiopathic or genetic, which means, you cannot control it. However, you can ensure your child is healthy and reduce the risks of contracting this disease. If your child is suffering from nephrotic syndrome, be patient and understanding with the suffering child. In most cases, they will outgrow it when they reach their late teens or adulthood.
Many children will outgrow nephrotic syndrome when they reach their teens. Children who suffer from an aggressive type of this syndrome may require lifelong medications and follow-up care.
No, congenital nephrotic syndrome is very rare. In most cases, it affects only one child.
Sindhuja, a mother of two, is an obsessive mom with a keen interest in psychology, especially child psychology. Her quest for knowledge and way with words led her to become a passionate content writer. She transformed her love for writing into a full-fledged career which incidentally also turned up being the perfect stress buster for the last 5 years.Read more.
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